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Hotel Vyvant

505 W Grape St
San Diego, CA 92101
(800) 518-9930 (Toll-Free)

(619) 230-1600
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Region: Downtown

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At Hotel Vyvant, we find tremendous joy in providing each and every guest with the kind of personalized experience and guest service that engages all the senses and makes travel memorable. Memorable as in, write-about-your-incredible-experience-in-your-travel-memoirs, worthy. That is our goal.

A hidden gem in the heart of San Diego's hip and historic Little Italy neighborhood, our hotel is inspired by the desire to create an experience that is reflective of its location, offering guests an authentically local experience through our comfortable vibe, sense of community and playful spirit.

Formerly the Little Italy Inn, Hotel Vyvant is just steps away from some of San Diego's favorite local restaurants, shops, galleries and hotspots and minutes from the San Diego Airport, Convention Center, the World-Famous San Diego Zoo, Sea World, Balboa Park, Gaslamp Quarter and the San Diego Harbor.

Located in a meticulously restored 1910 historical building, Hotel Vyvant offers the grace and elegance of a historic hotel, but all the modern amenities to make your stay superbly vyvant*. Our 23-room property is thoughtfully appointed with the finest furnishings, including uber comfy top-of-the-line beds, crisp linens and the fluffiest of fluffy bamboo cotton towels.

Upon arrival, you will be greeted by our warm and welcoming guest service associates whose exceptional attention to detail has helped us earn the #1 ranking of Overall Best Place to Stay in San Diego on We have also been honored by as one of the top three B&B/Inns in San Diego. We look forward to seeing you soon and helping you make your stay in San Diego your most memorable yet!

*[Vyvant: Vy-vant [Vai - vahnt] adjective 1. vibrancy of life; 2. of, or pertaining to good living; 3. enjoyment of living exceptionally well.]

Comfort Awaits You:

  • Select rooms with spa tubs or kitchenettes
  • Top-of-the-line beds and plush bamboo cotton towels
  • Premium memory foam mattresses in most rooms
  • We find joy in providing each and every guest with a personalized experience
  • Our desire is ensure that you have a lovely, warm & intimate lodging experience

Room Amenities:

  • Heat/air conditioning
  • Complimentary Wi-Fi
  • Complimentary in-room bottled water
  • Cable Television
  • In-room single-serve Keurig coffee & tea service
  • Complimentary Happy Hour on weekends

More Information

  • Destination Weddings
  • Free Wi-Fi
  • Indoor Corridor
  • Total Number of Kitchen Units: 5
  • Complimentary Breakfast