Laughter is indeed one of the best medicines, thanks to the endorphins it releases, and a visit to one of San Diego's comedy clubs will help get those mood enhancers flowing.
The American Comedy Co.
818 B 6th Avenue
San Diego, CA 92101
619-795-3858
Located in the heart of the Gaslamp Quarter in beautiful downtown San Diego, we provide the highest quality entertainment in an intimate, 200 seat venue with an old-city, speak-easy feel.
National Comedy Theatre
3717 India Street
619-295-4999
Improvisational comedy and interactive entertainment appropriate for all ages in the style of "Whose Line Is It Anyway?"
The Comedy Club at Pechanga
4500 Pechanga Parkway
Temecula, CA 92592
888-732-4264
The Comedy Club at the Pechanga Resort & Casino includes VIP-seating and full bar. Must be 21 or older.
Sycuan Live & Up Close
3007 Dehesa Road
El Cajon, CA 92019
800-457-5568
The Sycuan Live & Up Close showroom at Sycuan Casino is the setting for hilarious comedy performances . A good time and plenty of laughs are a sure bet! Check website for show listings.
4th & B
345 B St, Downtown
San Diego, CA 92101
619-231-4343
Features various comedians several times a month. Please check the performance calendar for upcoming performances. Must be 21 or older.
The Comedy Store
916 Pearl St
San Diego, CA 92037
858-454-9176
The Comedy store features comedy performances seven days a week and has hosted such famous comedians as David Letterman, Garry Shandling and Pauly Shore. Two drink minimum. Must be 21 or older.
The Mad House Comedy Club
502 Horton Plaza
San Diego, CA 92101
619-702-6666
The Mad House is a premiere comedy club, with live stand-up comedy featuring national headliners. Open 7 nights a week. Open mic early shows nightly.
Open Mic Amateur Comedy Jams
Lestat’s Coffee House
3343 Adams Ave, Normal Heights
Monday nights, cost if free. The show starts at 6:30 PM. It’s a small space so get their early if you want a seat.
Winston’s
1921 Bacon Street, Ocean Beach
Friday nights, $5 cover charge. The show starts at 7:00 PM. Run as a comedy “contest” where the audience participates in the voting.
Home & Away
2222 San Diego Avenue, Old Town
Every other Wednesday, cost is Free. The show starts at 8:30. It’s a small space so often standing room only.
Once you've laughed 'til it hurts, expand your nighttime entertainment plans to include a red-hot downtown nightclub or live musical performance at venues around San Diego County.
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